HCID 67483831, compound → HCID 53697139, compound

HRID 324846Notes

Reaction equation

HRID 324846 reaction equation
[CH:1]([C:4]1[C:9]([C:10](OCC)=[O:11])=[C:8]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[F:21])[C:7]([CH:22]=[CH:23][CH2:24][CH2:25][CH3:26])=[C:6]([CH:27]([CH3:29])[CH3:28])[N:5]=1)([CH3:3])[CH3:2]>C(OCC)(=O)C.CCCCCC>[CH:1]([C:4]1[C:9]([CH2:10][OH:11])=[C:8]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[F:21])[C:7]([CH:22]=[CH:23][CH2:24][CH2:25][CH3:26])=[C:6]([CH:27]([CH3:28])[CH3:29])[N:5]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 1

HCID 67483831HCID 67483831, compound

Product 1

HCID 53697139HCID 53697139, compound

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

The title compound was prepared from the intermediate obtained in Step A by the procedure described in Example 125, Step F. 1H NMR (300 MHz, CDCl3) (reported as a mixture of olefin isomers): δ 0.69-0.82 (m, 3 H), 1.09-1.40 (m, 14 H), 1.90 (m, 2 H), 3.20-3.45 (m, 2 H), 4.40 (m, 2 H), 5.25-5.45 (m, 1 H), 6.08 (m, 1H), 7.08-7.41 (m, 5 H). Rf=0.24 (10% ethyl acetate/n-hexane).

Sources & evidence

ORD record
ord-ef5fd5b41e3f43feb718686dc6ae0f13
Source dataset
uspto-grants-2001_04
Patent number
US06218431B1

Reaction notes

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