HCID 67483422, compound → HCID 54345918, compound

HRID 324858Notes

Reaction equation

HRID 324858 reaction equation
[CH:1]([C:4]1[C:9]([C:10](OCC)=[O:11])=[C:8]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([O:21][CH2:22][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH:16]=2)[C:7]([CH:29]=[CH:30][CH2:31][CH2:32][CH3:33])=[C:6]([CH:34]([CH3:36])[CH3:35])[N:5]=1)([CH3:3])[CH3:2]>C(OCC)(=O)C.CCCCCC>[CH:1]([C:4]1[C:9]([CH2:10][OH:11])=[C:8]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([O:21][CH2:22][C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=3)[CH:16]=2)[C:7]([CH:29]=[CH:30][CH2:31][CH2:32][CH3:33])=[C:6]([CH:34]([CH3:35])[CH3:36])[N:5]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 1

HCID 67483422HCID 67483422, compound

Product 1

HCID 54345918HCID 54345918, compound

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

The title compound was prepared from the intermediate obtained in Step A by the procedure described in Example 125, Step F. 1H NMR (300 MHz, CDCl3) (reported as a mixture of olefin isomers): δ 0.74 (t, J=7.4 Hz, 3 H), 1.25 (m, 14 H), 1.90 (m, 2 H), 3.39 (m, 2 H), 4.39 (d, J=6.0 Hz, 2 H), 5.07 (s, 2 H), 5.32 (m, 1 H), 5.97 (m, 1 H), 6.74 (m, 2 H), 6.95 (m, 1 H), 7.35 (m, 7 H). FAB-MS: calculated for C30H37NO2, 444; found 444 (M+H, 100%). Elemental analysis: calculated for C30H37NO2: C 81.22; H 8.41; N 3.16, found: C 80.51; H 8.41; N 3.36. Rf 0.5 (25% ethyl acetate/n-hexane).

Sources & evidence

ORD record
ord-a6cc1cc27702417d82f89f2df4f39a7a
Source dataset
uspto-grants-2001_04
Patent number
US06218431B1

Reaction notes

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