Phenoxyacetic Acid → Phenoxyacetyl chloride

HRID 324914Notes

Reaction equation

HRID 324914 reaction equation
[O:1]([CH2:8][C:9]([OH:11])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:14])=O>>[O:1]([CH2:8][C:9]([Cl:14])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 19188Phenoxyacetic AcidHCID 24386Thionyl Chloride

Product 1

HCID 69703Phenoxyacetyl chloride

Procedure

Phenoxyacetic acid (d5) was treated with 25 ml of thionyl chloride and stirred for 18 hours at room temperature. After the 5 end of the reaction, the reaction mixture was concentrated under vacuum at 300 C to provide phenoxyacetyl chloride (4.8 g).

Workup

  1. customAfter the 5 end of the reaction
  2. concentrationthe reaction mixture was concentrated under vacuum at 300 C

Sources & evidence

ORD record
ord-8715d0b84f814f46a2b1c5e81a732046
Source dataset
uspto-grants-2001_04
Patent number
US06221335B1

Reaction notes

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