HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 22001504, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Phenol | HCID 996 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 22001501 | HCID 22001501 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 22001504 | HCID 22001504 | 69.3% |
Reaction Steps
A solution of 100 mg of 4-fluoro-N-indan-1-yl-3-(3-methyl-butylsulfamoyl)benzamide (Example 41), 26 mg of phenol, and 100 mg of potassium carbonate in 4 ml of N,N-dimethylacetamide was heated to 100° C. for 6 h. After water had been added and the precipitated product filtered off with suction, 82 mg of 4-phenoxy-N-indan-1-yl-3-(3-methyl-butylsulfamoyl)benzamide were obtained; m.p. 73° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06221866B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-c42add06fbfc427d8b3589569a88a26c |
| Source note | uspto-grants-2001_04 |