6-Methoxy-3-pyridinylamine → N-(6-methoxypyridin-3-yl)-3-dimethylamino-1,2,3,4-tetrahydro-9H-carbazole-6-carboxamide

HRID 325000Notes

Reaction equation

HRID 325000 reaction equation
[CH3:1][N:2]([CH3:19])[CH:3]1[CH2:15][C:14]2[C:13]3[C:8](=[CH:9][CH:10]=[C:11]([C:16]([OH:18])=O)[CH:12]=3)[NH:7][C:6]=2[CH2:5][CH2:4]1.[CH3:20][O:21][C:22]1[N:27]=[CH:26][C:25]([NH2:28])=[CH:24][CH:23]=1>>[CH3:20][O:21][C:22]1[N:27]=[CH:26][C:25]([NH:28][C:16]([C:11]2[CH:12]=[C:13]3[C:8](=[CH:9][CH:10]=2)[NH:7][C:6]2[CH2:5][CH2:4][CH:3]([N:2]([CH3:1])[CH3:19])[CH2:15][C:14]3=2)=[O:18])=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 811216-Methoxy-3-pyridinylamineHCID 123618113-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxylic acid

Product 1

HCID 15512580N-(6-methoxypyridin-3-yl)-3-dimethylamino-1,2,3,4-tetrahydro-9H-carbazole-6-carboxamideYield 14%

Procedure

Beginning with 7.4 mg (0.029 mMol) 3-dimethylamino-1,2,3,4-tetrahydro-9H-carbazole-6-carboxylic acid and 6-methoxy-3-aminopyridine, 1.8 mg (14%) of the title compound were recovered.

Sources & evidence

ORD record
ord-1abfbf5b63884bfcb456437a929ba610
Source dataset
uspto-grants-2001_04
Patent number
US06221884B1

Reaction notes

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