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HRID325097

反应详情

EQUATION

反应方程式

HRID 325097 的结构方程式

REACTANTS

反应物

2
结构：Cc1c(C)c2c(c(C)c1O)CC[C@@](C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O2
HCID14985

alpha-Vitamin E

C29H50O2

结构：Nc1ccc(C(=O)Cl)cc1
HCID177720

Benzoyl chloride, 4-amino-

C7H6ClNO

PRODUCTS

生成物

1
结构：Cc1c(C)c2c(c(C)c1O)CC[C@@](C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O2.Nc1ccc(C(=O)[O-])cc1
HCID86756642

未命名化合物

收率 68%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CN(C)c1ccncc1
催化剂HCID14284

N,N-Dimethylpyridin-4-amine

C7H10N2

结构：c1ccncc1
溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

The reaction of alpha-tocopherol with 4-aminobenzoic acid chloride was carried out in the same manner with Example I, except that 10 mol % of 4-(dimethylamino)pyridine was added together with pyridine. This reaction was confirmed to proceed in a similar pattern to that of Example I as measured by thin layer chromatography. The remaining processes of Example I were repeated to produce alpha-tocopherol 4-aminobenzoate (0.61 g, yield 68%).