HCID 11459419, compound → HCID 18371077, compound

HRID 325131Notes

Reaction equation

HRID 325131 reaction equation
C[O:2][C:3](=[O:18])[CH2:4][C:5](=[O:17])[CH2:6][CH2:7][CH:8]1[C:13]([CH3:15])([CH3:14])[CH2:12][CH2:11][CH:10]=[C:9]1[CH3:16]>C(O)CO>[O:17]=[C:5]([CH2:6][CH2:7][CH:8]1[C:13]([CH3:15])([CH3:14])[CH2:12][CH2:11][CH:10]=[C:9]1[CH3:16])[CH2:4][C:3]([OH:18])=[O:2]

Participants

3

Reactant 1

HCID 11459419HCID 11459419, compound

Product 1

HCID 18371077HCID 18371077, compound

Reagents, catalysts & solvents 1

HCID 174Ethylene GlycolSolvent

Conditions

Temperature
180 °C

Procedure

A mixture of 25.2 g 3-oxo-5-(2,6,6-trimethyl-cyclohex-2-enyl)-pentanoic acid methyl ester and 4.3 g ethylene glycol was slowly heated to 180° C. while distilling off methanol. On completion, the reaction mixture was chromatographed over silica gel to yield a colourless liquid.

Workup

  1. distillationwhile distilling off methanol
  2. customOn completion, the reaction mixture was chromatographed over silica gel
  3. customto yield a colourless liquid

Sources & evidence

ORD record
ord-727795adb21c4862b3feb333b7425f83
Source dataset
uspto-grants-2001_04
Patent number
US06222062B1

Reaction notes

Loading…