Allyl Alcohol → 2-(3-hydroxypropyl)cyclododecanone

HRID 325142Notes

Reaction equation

HRID 325142 reaction equation
[C:1]1(=[O:13])[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:14]([OH:17])[CH:15]=[CH2:16].C(OOC(C)(C)C)(C)(C)C>>[OH:17][CH2:14][CH2:15][CH2:16][CH:2]1[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:1]1=[O:13]

Participants

4

Reactant 3

HCID 7858Allyl AlcoholHCID 8033Di-tert-butyl peroxideHCID 13246Cyclododecanone

Product 1

HCID 101309872-(3-hydroxypropyl)cyclododecanone

Procedure

From a double-walled vessel made of glass, whose temperature is thermostatically controlled at 100° C. and which is fitted with a magnetic stirrer and serves as the storage container for the cyclododecanone, 400 g/h are pumped to a mixing column which is kept at a temperature of 100° C. 21.4 g/h of a mixture of allyl alcohol (12.2 g/h) and di-tert-butyl peroxide (9.2 g/h) are continuously metered into the feedline of the mixing column.

Workup

  1. customFrom a double-walled vessel made of glass, whose temperature
  2. customis thermostatically controlled at 100° C.
  3. customwhich is fitted with a magnetic stirrer
  4. customis kept at a temperature of 100° C

Sources & evidence

ORD record
ord-abd32300fe634caea9c40bbcd4ac32fb
Source dataset
uspto-grants-2001_04
Patent number
US06222076B1

Reaction notes

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