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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 325274Generated: October 25, 2026

Acetic Anhydride → N-acetoacetyl-L-aspartic anhydride

https://huagongshe.com/reaction/325274

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AnhydrideHCID 7918—
ReactantMagnesium AcetateHCID 8896—
ReactantN-acetoacetylaspartic acidHCID 13334672—
SolventEthyl AcetateHCID 8857—
ProductN-acetoacetyl-L-aspartic anhydrideHCID 13334674—

Reaction Conditions

Temperature55 °C

Reaction Steps

21.72 parts of N-acetoacetyl-L-aspartic acid, 0.14 parts of magnesium acetate, and 9.5 parts by volume of acetic anhydride were mixed with 200 parts by volume of ethyl acetate and heated at 55±2° C. under argon for 24 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04440677
Source datasetuspto-grants-1984_04
ORD IDord-f65be8cf1ac34fd49f886e0589365cbc
Source noteuspto-grants-1984_04