HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178488775, compound → 2-(3-Pyridyl)-4-(4-hydroxyphenyl)imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178488775 | HCID 178488775 | — |
| Solvent | Hydrogen Bromide | HCID 260 | — |
| Product | 2-(3-Pyridyl)-4-(4-hydroxyphenyl)imidazole | HCID 178515885 | — |
Reaction Steps
A mixture of 4-(p-methoxyphenyl)-2-(3-pyridyl)imidazole (2.0 g.) and 48% HBr (100 ml.) is heated to reflux for 20 hrs. After cooling, the precipitate is filtered off and crystallized from isopropanol-methanol to give 2.05 g. of 2-(3-pyridyl)-4-(4-hydroxyphenyl)imidazle of m.p. 315°-318° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04440774 |
| Source dataset | uspto-grants-1984_04 |
| ORD ID | ord-ebe3842b9a18461ab677b21626116f6d |
| Source note | uspto-grants-1984_04 |