Hydrochloric Acid → HCID 13309895, compound

HRID 325446Notes

Reaction equation

HRID 325446 reaction equation
C([O:3][C:4]([C:6]1[N:7]=[CH:8][N:9]2[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[NH:12][C:11](=[O:19])[C:10]=12)=[O:5])C.Cl>[OH-].[Na+]>[O:19]=[C:11]1[NH:12][C:13]2[C:18](=[CH:17][CH:16]=[CH:15][CH:14]=2)[N:9]2[CH:8]=[N:7][C:6]([C:4]([OH:5])=[O:3])=[C:10]12

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 13309870HCID 13309870, compound

Product 1

HCID 13309895HCID 13309895, compoundYield 96.2%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

4-Oxo-4,5-dihydroimidazo[1,5-a]quinoxaline 3-carboxylic acid ethyl ester (3.5 g) was dissolved in 100 ml of 0.5 N sodium hydroxide solution. The solution was heated on steam bath for one hour, cooled to room temperature, then acidified by concentrated hydrochloric acid (5 ml). The product precipitated out as a white solid (3.0 g, 95% yield), m.p. >300° C.

Workup

  1. temperatureThe solution was heated on steam bath for one hour

Sources & evidence

ORD record
ord-d3f8c18c1cfd4a3ca9f740e6dcc13d0e
Source dataset
uspto-grants-1984_04
Patent number
US04440929

Reaction notes

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