反应详情

A methanolic solution of the product prepared in Step A was diluted to 100 ml and 12.4 ml of concentrated HCl was added. The solution was stirred at ambient temperature for 18 hours, concentrated, and the residue was dissolved in 80 ml of water and extracted twice with CH2Cl2. The aqueous layer was concentrated, treated with n-propanol and concentrated under high vacuum to give the title compound as a foam.

1. additionwas added
2. concentrationconcentrated
3. dissolutionthe residue was dissolved in 80 ml of water
4. extractionextracted twice with CH2Cl2
5. concentrationThe aqueous layer was concentrated
6. additiontreated with n-propanol
7. concentrationconcentrated under high vacuum