Glycerol → HCID 70506550, compound

HRID 325544Notes

Reaction equation

HRID 325544 reaction equation
[CH2:1]([NH:15][C:16]1[CH:17]=[C:18]([CH:22]([CH2:27][CH3:28])[C:23]([O:25][CH3:26])=[O:24])[CH:19]=[CH:20][CH:21]=1)[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].[OH:29][CH2:30][CH:31](CO)[OH:32]>>[CH2:1]([NH:15][C:16]1[CH:17]=[C:18]([CH:22]([CH2:27][CH3:28])[C:23]([O:25][CH2:26][CH:31]([OH:32])[CH2:30][OH:29])=[O:24])[CH:19]=[CH:20][CH:21]=1)[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Participants

3

Reactant 2

HCID 753GlycerolHCID 70507109HCID 70507109, compound

Product 1

HCID 70506550HCID 70506550, compound

Conditions

Temperature
180 °C

Procedure

A mixture of 2.25 g. of methyl 3-(4-tetradecenylamino)phenylbutyrate, 280 mg. of glycerol, and 1.37 g. of p-touluenesulfonic acid is heated at 180° C. for 18 hours and then is partitioned between ether and 3% aqueous sodium carbonate solution. The ether layer is separated, dried, and evaporated to yield the product as a white solid.

Workup

  1. additionA mixture of 2.25 g
  2. customis partitioned between ether and 3% aqueous sodium carbonate solution
  3. customThe ether layer is separated
  4. customdried
  5. customevaporated

Sources & evidence

ORD record
ord-997f2b9ea3be40d089a02ce41988bc87
Source dataset
uspto-grants-1984_04
Patent number
US04440940

Reaction notes

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