HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 178519811, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | HCID 178516425 | HCID 178516425 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 178519811 | HCID 178519811 | — |
Reaction Steps
A mixture of 4-hydroxy-7-trifluoromethylquinoline (30.0 g.), 40% aqueous formaldehyde solution (36 ml.) and 1 M aqueous sodium hydroxide solution (250 ml.) was stirred at 40°-50° for 8 hours. The solid product was collected and dried to give the novel 4-hydroxy-3-hydroxymethyl-7-trifluoromethylquinoline, m.p. 302°-304°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04442109 |
| Source dataset | uspto-grants-1984_04 |
| ORD ID | ord-15329c99661a47ca995ee2271acef378 |
| Source note | uspto-grants-1984_04 |