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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 325637Generated: October 30, 2026

Formaldehyde → HCID 178519817, compound

https://huagongshe.com/reaction/325637

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantDichloromethaneHCID 6344—
ReactantHCID 178516458HCID 178516458—
SolventSodium HydroxideHCID 14798—
ProductHCID 178519817HCID 178519817—

Reaction Steps

8-Fluoro-4-hydroxyquinoline was reacted with formaldehyde in aqueous sodium hydroxide to give the novel compound 8-fluoro-4-hydroxy-3-hydroxymethylquinoline, m.p. 176°-178° (from dichloromethane).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04442109
Source datasetuspto-grants-1984_04
ORD IDord-38970286e84a46cb833b9fa2152239f6
Source noteuspto-grants-1984_04