Formaldehyde → HCID 178423369, compound

HRID 325639Notes

Reaction equation

HRID 325639 reaction equation
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([CH3:12])[CH:10]=2)[N:5]=[CH:4][CH:3]=1.[CH2:13]=[O:14]>[OH-].[Na+]>[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([CH3:12])[CH:10]=2)[N:5]=[CH:4][C:3]=1[CH2:13][OH:14]

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 178423367HCID 178423367, compound

Product 1

HCID 178423369HCID 178423369, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

4-Hydroxy-6-methylquinoline was reacted with formaldehyde in aqueous sodium hydroxide at 40°-45° for 60 hours to give the novel compound 4-hydroxy-3-hydroxymethyl-6-methylquinoline, m.p. 188°-189° (dec.).

Sources & evidence

ORD record
ord-4dd3c6390aeb4117b664a9ad5983c0a0
Source dataset
uspto-grants-1984_04
Patent number
US04442109

Reaction notes

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