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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 325639Generated: October 28, 2026

Formaldehyde → HCID 178423369, compound

https://huagongshe.com/reaction/325639

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantHCID 178423367HCID 178423367—
SolventSodium HydroxideHCID 14798—
ProductHCID 178423369HCID 178423369—

Reaction Steps

4-Hydroxy-6-methylquinoline was reacted with formaldehyde in aqueous sodium hydroxide at 40°-45° for 60 hours to give the novel compound 4-hydroxy-3-hydroxymethyl-6-methylquinoline, m.p. 188°-189° (dec.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04442109
Source datasetuspto-grants-1984_04
ORD IDord-4dd3c6390aeb4117b664a9ad5983c0a0
Source noteuspto-grants-1984_04