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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 325645Generated: October 29, 2026

Formaldehyde → HCID 178519815, compound

https://huagongshe.com/reaction/325645

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantMethanolHCID 887—
ReactantHCID 178516443HCID 178516443—
SolventSodium HydroxideHCID 14798—
ProductHCID 178519815HCID 178519815—

Reaction Steps

8-Chloro-4-hydroxyquinoline was reacted with formaldehyde in aqueous sodium hydroxide to give the novel compound 8-chloro-4-hydroxy-3-hydroxymethylquinoline, m.p. >300° (from methanol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04442109
Source datasetuspto-grants-1984_04
ORD IDord-0a10780eddbb4c2f8da35ab09497dbe3
Source noteuspto-grants-1984_04