Dimethyl Sulfate → HCID 12807841, compound

Participants

Reaction Steps

Dimethyl sulphate (3.0 ml.) was added to a stirred solution of 4-hydroxy-3-methylsulphonylmethylquinoline (1.9 g.) and potassium hydroxide (1.4 g.) in water (20 ml.) at 5°. The mixture was stirred at room temperature for 4 hours, then filtered to give the novel 1-methyl-3-methylsulphonylmethyl-4-quinolone, m.p. 204°-205° (from acetone).

Provenance & Evidence