Acetic Acid → HCID 20463959, compound

Participants

Reaction Steps

10 ml of acetic acid and 0.46 ml of acetic anhydride are added to 1.5 g of 2-dipropylamino-5-amino-6-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide (obtained in accordance with Example 1(d)) in 25 ml of methylene chloride at 0° C. The mixture is stirred for one hour, diethyl ether is added and the solid is recrystallised from ethanol. This gives 1.2 g of a product melting at 244.5° C.

Provenance & Evidence