Hydrochloric Acid → 2-(4-Methoxybenzyl)-2h-tetrazole-5-carboxylic acid

Participants

Reaction Steps

Potassium 2-(4-methoxybenzyl)-2H-tetrazole-5-carboxylate (2.45 g) was dissolved in a minimum quantity of water and acidified to pH 1 by treatment with concentrated hydrochloric acid. The mixture was stirred for 3 hours, and then the solid was filtered off and washed with water to give 2-(4-methoxybenzyl)-2H-tetrazole-5-carboxylic acid (1.20 g), m.p. 146°-147° C. (with decomposition).

Provenance & Evidence