反应详情

With the use of the apparatus described in Example 1, 143.6 g (1 mol) of 4-chloro-2-aminophenol and 181.3 g (1.02 mols) of potassium methyl xanthate (90%) in 500 ml of water were refluxed. The reaction was complete within 3 hours. The dark reaction solution was acidified with concentrated hydrochloric acid, the precipitate was suction-filtered and washed neutral with water. After drying in vacuo at 80° C., 179 g (96.7% of th.) of 5-chloro-2-mercaptobenzoxazole having a melting point of 269°-271° C. were obtained.

1. temperaturewere refluxed
2. filtrationthe precipitate was suction-filtered
3. washwashed neutral with water
4. customAfter drying in vacuo at 80° C.