4-Bromobenzaldehyde → N-[(4-bromophenyl)(toluene-4-sulfonyl)methyl]formamide

HRID 32577Notes

Reaction equation

I[C:2]1[CH:3]=[C:4]([CH:8]([NH:19][CH:20]=[O:21])[S:9]([C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][CH:13]=2)(=[O:11])=[O:10])[CH:5]=[CH:6][CH:7]=1.[Br:22]C1C=CC(C=O)=CC=1>>[Br:22][C:7]1[CH:6]=[CH:5][C:4]([CH:8]([NH:19][CH:20]=[O:21])[S:9]([C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][CH:13]=2)(=[O:11])=[O:10])=[CH:3][CH:2]=1

Participants

Reactant 2

HCID 707414-Bromobenzaldehyde

HCID 85929703{(3-Iodophenyl)[(4-methylphenyl)sulfonyl]methyl}formamide

Product 1

HCID 12181677N-[(4-bromophenyl)(toluene-4-sulfonyl)methyl]formamide

Procedure

The title compound was prepared by a similar process to that described for Intermediate 52 but using 4-bromobenzaldehyde in place of 3-iodobenzaldehyde. Solid (31 g, 80%);

Sources & evidence

ORD record: ord-3d17fd2184ec4c0da700016a6a5861ac
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07427616B2

Reaction notes

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