Thionyl Chloride → 4-Benzyloxybenzoylchloride

HRID 325789Notes

Reaction equation

HRID 325789 reaction equation
[CH2:1]([O:8][C:9]1[CH:17]=[CH:16][C:12]([C:13](O)=[O:14])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:20])=O>ClC=C(Cl)Cl>[CH2:1]([O:8][C:9]1[CH:17]=[CH:16][C:12]([C:13]([Cl:20])=[O:14])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 738804-(Benzyloxy)benzoic acid

Product 1

HCID 37664104-Benzyloxybenzoylchloride

Reagents, catalysts & solvents 1

HCID 6575TrichloroethyleneSolvent

Procedure

A solution of 164.7 g 4-benzyloxybenzoic acid obtained in step (a) and 80 ml of thionyl chloride in 750 ml of trichloroethylene was refluxed with stirring for 3 hrs. The crystalline residue obtained after evaporation was recrystallized from petroleum ether b.p. 80°-110° C.

Workup

  1. customThe crystalline residue obtained
  2. customafter evaporation
  3. customwas recrystallized from petroleum ether b.p. 80°-110° C.

Sources & evidence

ORD record
ord-1f4a1844baf04466957b01d2accc73de
Source dataset
uspto-grants-1984_04
Patent number
US04442300

Reaction notes

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