Hydrochloric Acid → 2,6-Dichlorobenzylglyoxal

HRID 325949Notes

Reaction equation

HRID 325949 reaction equation
C([O:3][C:4](OCC)([CH2:7][C:8]1[C:13]([Cl:14])=[CH:12][CH:11]=[CH:10][C:9]=1[Cl:15])[CH:5]=[O:6])C.Cl>C(O)C>[Cl:14][C:13]1[CH:12]=[CH:11][CH:10]=[C:9]([Cl:15])[C:8]=1[CH2:7][C:4]([CH:5]=[O:6])=[O:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 204632942,6-Dichlorobenzylglyoxal diethylacetal

Product 1

HCID 204633232,6-Dichlorobenzylglyoxal

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 10 g of 2,6-dichlorobenzylglyoxal diethylacetal, 40 ml of ethanol and 20 ml of concentrated hydrochloric acid is refluxed for 4 hours and then is evaporated to dryness. The residue, which is a yellowish oil, consists of crude 2,6-dichlorobenzylglyoxal and is used in step (b) of this Example as set forth below.

Workup

  1. temperatureis refluxed for 4 hours
  2. customis evaporated to dryness

Sources & evidence

ORD record
ord-4719f1c3bcbc45e78fa6c683064271c8
Source dataset
uspto-grants-1984_04
Patent number
US04443466

Reaction notes

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