Benzyl chloroformate → HCID 20463208, compound

HRID 325961Notes

Reaction equation

HRID 325961 reaction equation
[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[O:12][CH:13]1[CH2:18][CH2:17][N:16](C)[CH2:15][CH2:14]1.[Cl:20][C:21]([O:23][CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)=[O:22]>>[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[O:12][CH:13]1[CH2:18][CH2:17][N:16]([C:21]([O:23][CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[O:22])[CH2:15][CH2:14]1.[ClH:20].[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[O:12][CH:13]1[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]1

Participants

4

Reactant 2

HCID 10387Benzyl chloroformateHCID 20463216HCID 20463216, compound

Product 2

HCID 20463208HCID 20463208, compoundHCID 20463262HCID 20463262, compound

Procedure

When in the procedure of Example 11 4-(1-methyl-2-naphthalenyloxy)-1-methylpiperidine is reacted with benzyl chloroformate, the resulting 4-(1-methyl-2-naphthalenyloxy)-1-(phenylmethoxycarbonyl)piperidine yields upon hydrolysis 4-(1-methyl-2-naphthalenyloxy)piperidine hydrochloride.

Sources & evidence

ORD record
ord-b921fe349b194cfea75c2487bc10d98e
Source dataset
uspto-grants-1984_04
Patent number
US04443462

Reaction notes

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