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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 325963Generated: October 26, 2026

3,4'-Dichloropropiophenone → 3-[4-(5-Methoxy-1-naphthalenyloxy)-1-piperidyl]-1-(4-chlorophenyl)-1-propanone hydrochloride

https://huagongshe.com/reaction/325963

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4'-DichloropropiophenoneHCID 77550—
Reactant4-ChlorobutyrophenoneHCID 253533—
Reactant2-Naphthyl 4-Piperidinyl Ether HydrochlorideHCID 18423350—
Reactant4-(5-Methoxy-1-naphthalenyloxy)piperidine hydrochlorideHCID 20463230—
Product3-[4-(5-Methoxy-1-naphthalenyloxy)-1-piperidyl]-1-(4-chlorophenyl)-1-propanone hydrochlorideHCID 20463225—

Reaction Steps

When in the procedure of Example 13, 4-(5-methoxy-1-naphthalenyloxy)piperidine hydrochloride is substituted for 4-(2-naphthalenyloxy)piperidine hydrochloride and 3-chloro-1-(4-chlorophenyl)-1-propanone substituted for 4-chloro-1-phenyl-1-butanone, 3-[4-(5-methoxy-1-naphthalenyloxy)-1-piperidyl]-1-(4-chlorophenyl)-1-propanone hydrochloride is produced.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04443462
Source datasetuspto-grants-1984_04
ORD IDord-14c4f3bdc3a64a6bbb4be51aaf7e57d7
Source noteuspto-grants-1984_04