HCID 20461931, compound → HCID 20461932, compound

Participants

Reaction Steps

A mixture of 12.6 g of 2.5-bis(difluoromethoxy)nitrobenzene, 1.3 g of Raney-nickel catalyst and 130 ml of dioxane is agitated in a hydrogen atmosphere for 15 hours at a temperature of 20°-25° C. The hydrogen consumption is 3.34 liters. After removal of the catalyst the mixture is evaporated to dryness, yielding 11.0 g of crude 2.5-bis(difluoromethoxy) aniline in form of a yellow-brown oil.

Provenance & Evidence