Gamma-Butyrolactone → 1-Decylpyrrolidin-2-one

HRID 326065Notes

Reaction equation

HRID 326065 reaction equation
[C:1]1(=[O:6])O[CH2:4][CH2:3][CH2:2]1.[CH2:7]([NH2:17])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]>>[CH2:7]([N:17]1[CH2:4][CH2:3][CH2:2][C:1]1=[O:6])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Participants

3

Reactant 2

HCID 7302Gamma-ButyrolactoneHCID 8916Decylamine

Product 1

HCID 1714271-Decylpyrrolidin-2-oneYield 83.1%

Procedure

18.8 g (0.22 M) of γ-butyrolactone and 34.6 g (0.22 M) of n-decylamine were mixed and heated to 180° in a round bottom flask equipped with a condenser and a Dean-Stark trap for 22 hours. The dark brown reaction mixture was distilled at reduced pressure to yield 40.9 g (82.5%) of colorless product; b.p. 150°-155°/0.5-1 mm.

Workup

  1. temperatureheated to 180° in a round bottom flask
  2. customequipped with a condenser
  3. distillationThe dark brown reaction mixture was distilled at reduced pressure

Sources & evidence

ORD record
ord-f9057b6ea81a43d9b8453cec614bc15e
Source dataset
uspto-grants-1984_04
Patent number
US04444762

Reaction notes

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