Benzaldehyde → HCID 67857123, compound

HRID 326219Notes

Reaction equation

HRID 326219 reaction equation
C1([CH:7]2[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=3[CH2:12][NH:11][CH2:10][CH2:9][NH:8]2)C=CC=CC=1.C(=O)C1C=CC=CC=1>C(O)C>[CH:7]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[CH2:12][NH:11][CH:10]=[CH:9][N:8]=1

Participants

4

Reactant 2

HCID 240BenzaldehydeHCID 13279663HCID 13279663, compound

Product 1

HCID 67857123HCID 67857123, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 2 g (8.4 mmol) of 1,2,3,4,5,6-hexahydro-1-phenyl-2,5-benzodiazocine and 1.0 g (9.2 mmol) of benzaldehyde in 40 mL of ethanol was refluxed for 30 min, cooled on ice and the product filtered off. There was obtained 2.33 g of 3,4-dihydro-1,11-diphenyl-2,5-methano-1,H, 6H-2,5-benzodiazocine, mp 175°-176°.

Workup

  1. temperaturewas refluxed for 30 min
  2. temperaturecooled on ice
  3. filtrationthe product filtered off

Sources & evidence

ORD record
ord-30fa4774483b471ea0ddbaaff6e8a414
Source dataset
uspto-grants-1993_12
Patent number
US05268372

Reaction notes

Loading…