Potassium Iodide → 6-(2-Aminoethyl)-2H-1,4-benzoxazin-3(4H)-one

HRID 326247Notes

Reaction equation

Br[CH2:2][CH2:3][C:4]1[CH:5]=[CH:6][C:7]2[O:12][CH2:11][C:10](=[O:13])[NH:9][C:8]=2[CH:14]=1.[I-].[K+].C[N:18](C)C=O>>[NH2:18][CH2:2][CH2:3][C:4]1[CH:5]=[CH:6][C:7]2[O:12][CH2:11][C:10](=[O:13])[NH:9][C:8]=2[CH:14]=1

Participants

Reactant 3

HCID 4875Potassium Iodide

HCID 6228Dimethylformamide

HCID 14995354HCID 14995354, compound

Product 1

HCID 149953836-(2-Aminoethyl)-2H-1,4-benzoxazin-3(4H)-one

Procedure

In a 250-cm3 ground-necked flask, 0.01 mol of 6-(2-bromoethyl)-3-oxo-2,3-dihydro-1,4-benzoxazine and 0.3 g of potassium iodide are dissolved in 30 cm3 of dimethylformamide.

Sources & evidence

ORD record: ord-42f9c3eefd7c4c78bf4f911a16480b7d
Source dataset: uspto-grants-1993_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05268381

Reaction notes

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