Potassium Carbonate → HCID 54440903, compound

Participants

Reaction Steps

According to the same procedure as in Preparation 46, a mixture of 5,7-dihydroxyspiro[2H-1-benzopyran-2,1'-cyclohexan]-4(3H)-one (prepared in Preparation 19) (0.248 g, 1.0 mmol), ethyl 4-bromobutyrate (0.215 g, 1.1 mmol), anhydrous potassium carbonate (0.207 g, 1.5 mmol), and acetonitrile (3 ml) is reacted and treated. The resulting extract is concentrated and the residue is purified by a silica gel column chromatography (eluent: acetone and dichlomethane, 1:50) to obtain the title compound as an oil (0.236 g, yield 64.9%).

Provenance & Evidence