反应详情

A solution of benzoyl chloride (2.94 g, 0.021 mole) and 1-methylethyl 5-amino-2-chloro-4-fluorobenzoate (4.62 g, 0.020 mole) in methyl ethyl ketone (50 ml) was stirred at room temperature for 3 days. Evaporation of the solvent and crystallization of the solid residue from ethyl ether gave colorless needles, m.p. 117°-119° C. (6 g, 90% yield).

1. customEvaporation of the solvent and crystallization of the solid residue from ethyl ether
2. customgave colorless needles, m.p. 117°-119° C. (6 g, 90% yield)