HCID 22849140, compound → HCID 22849139, compound

HRID 326387Notes

Reaction equation

HRID 326387 reaction equation
C(OC([NH:8][C@@H:9]([CH2:25][CH:26]1[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1)[C@@H:10]([O:18]COCCOC)[C@@H:11]([OH:17])[CH2:12][N:13]([O:15][CH3:16])[CH3:14])=O)(C)(C)C>Cl.C(O)C>[NH2:8][C@@H:9]([CH2:25][CH:26]1[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1)[C@@H:10]([OH:18])[C@@H:11]([OH:17])[CH2:12][N:13]([O:15][CH3:16])[CH3:14]

Participants

3

Reactant 1

HCID 22849140HCID 22849140, compound

Product 1

HCID 22849139HCID 22849139, compound

Reagents, catalysts & solvents 1

HCID 21887872Ethanol hydrochlorideSolvent

Procedure

The resultant compound from Example 137 (1.00 mmol) was stirred for 1 h in 4M HCl/ethanol. The mixture was evaporated and the residue was dissolved in water which was made basic with solid K2CO3 and was then saturated with NaCl. The mixture was extracted with chloroform which was dried over Na2SO4 and evaporated to afford the desired product.

Workup

  1. customThe mixture was evaporated
  2. dissolutionthe residue was dissolved in water which
  3. extractionThe mixture was extracted with chloroform which
  4. dry with materialwas dried over Na2SO4
  5. customevaporated

Sources & evidence

ORD record
ord-d5fc7027a89c4eb38ceb99d84805527f
Source dataset
uspto-grants-1993_12
Patent number
US05268374

Reaction notes

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