Morpholine → 3,9-Dioxa-6-azoniaspiro[5.5]undecane, chloride

HRID 326403Notes

Reaction equation

[CH2:1]([O:4][CH2:5][CH2:6]Cl)[CH2:2][Cl:3].[NH:8]1[CH2:13][CH2:12][O:11][CH2:10][CH2:9]1>>[Cl-:3].[CH2:2]1[N+:8]2([CH2:13][CH2:12][O:11][CH2:10][CH2:9]2)[CH2:6][CH2:5][O:4][CH2:1]1

Participants

Reactant 2

HCID 8083Morpholine

HCID 8115Bis(2-chloroethyl) ether

Product 1

HCID 109323083,9-Dioxa-6-azoniaspiro[5.5]undecane, chloride

Procedure

In a preferred embodiment, 2,2'-dichlorodiethylether was reacted with morpholine to form 3,9-dioxa-6-azoniaspiro [5.5] undecane chloride as the intermediate.

Sources & evidence

ORD record: ord-75b583cb038149b1afd5bbbac6dabe39
Source dataset: uspto-grants-1993_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05268470

Reaction notes

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