Sulfuric Acid → 2-Propenamide, 2-methyl-, sulfate (1:1)

HRID 326429Notes

Reaction equation

[C:1]([O:6]C)(=O)[C:2]([CH3:4])=[CH2:3].CC(C)(O)C#[N:11].[S:14](=[O:18])(=[O:17])([OH:16])[OH:15]>>[S:14]([OH:18])([OH:17])(=[O:16])=[O:15].[C:1]([NH2:11])(=[O:6])[C:2]([CH3:4])=[CH2:3]

Participants

Reactant 3

HCID 1118Sulfuric Acid

HCID 6406Acetone Cyanohydrin

HCID 6658Methyl Methacrylate

Product 1

HCID 1201452-Propenamide, 2-methyl-, sulfate (1:1)

Procedure

Heretofore, an α,β-unsaturated carboxylic acid ester, for example, methyl methacrylate, has been produced by treating acetone cyanohydrin with concentrated sulfuric acid to form methacrylamide sulfate and esterifying it with methanol.

Sources & evidence

ORD record: ord-65d31ba1166143568dbb5c77b69ff30b
Source dataset: uspto-grants-1993_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05268503

Reaction notes

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