Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | 3,4-Difluorobenzenesulfonamide | HCID 822865 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 59793748 | HCID 59793748 | 86% |
Reaction Steps
A mixture of 0.5 g (3 mmol) 3,4-Difluoro-benzenesulfonamide and 1.15 g (13 mmol) piperazine in 2.3 ml water was heated to 110° C. for 3 h and subsequently the precipitate was filtered off and washed with water and toluene. The residue was dried under high vacuum to yield 0.578 g (86%) of the title compound as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07427612B2 |
|---|
| Source dataset | uspto-grants-2008_09 |
|---|
| ORD ID | ord-69429c3938ce42c1b39434de8f7af41c |
|---|
| Source note | uspto-grants-2008_09 |
|---|
