反应详情

温度

110 °C

A mixture of 0.5 g (3 mmol) 3,4-Difluoro-benzenesulfonamide and 1.15 g (13 mmol) piperazine in 2.3 ml water was heated to 110° C. for 3 h and subsequently the precipitate was filtered off and washed with water and toluene. The residue was dried under high vacuum to yield 0.578 g (86%) of the title compound as white crystals.

1. filtrationsubsequently the precipitate was filtered off
2. washwashed with water and toluene
3. customThe residue was dried under high vacuum