HCID 10611577, compound → HCID 19735076, compound

Participants

Reaction Steps

According to the same manner as that described in the preparation of Compound 1 in Example 1, 6-cyano-2,2-dimethyl-4-(1-methyl-2-oxopyrrolidin-3-yl)-2H-1,3-benzoxazine (Compound 15) was obtained except that N-methylpyrrolidone and a solution of 1.6M lithium diisopropylamide in a mixed solvent of tetrahydrofuran and hexane were used instead of 2-bromopyridine and the solution of 1.6M n-butyl lithium in hexane, respectively.

Provenance & Evidence