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HRID326625

反应详情

EQUATION

反应方程式

HRID 326625 的结构方程式

REACTANTS

反应物

2
结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：CCOC(=O)c1cc(=O)c2c(CC)cc(Br)cc2[nH]1
HCID19735211

未命名化合物

PRODUCTS

生成物

1
结构：CCc1cc(Br)cc2[nH]c(C(=O)O)cc(=O)c12
HCID14842736

未命名化合物

PROCEDURE

实验过程

Treatment of ethyl 7-bromo-5-ethyl-4-oxo-1,4-dihydroquinoline-2-carboxylate with sodium hydroxide (0.247 g), as described in Example 1c, gave 7-bromo-5-ethyl-4-oxo-1,4-dihydroquinoline-2-carboxylic acid, mp 278° C. (decomp.). δ (360 MHz, DMSO-d6) 1.14 (3H, t, CH3), 3.24 (2H, q, CH2), 6.55 (1H, s, 3-H), 7.22 (1H, d, 6-H), 8.02 (1H, d, 8-H) and 11.74 (1H, bs, NH).