HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 7-Bromo-5-ethyl-4-oxo-1,4-dihydroquinoline-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 7-bromo-5-ethyl-4-oxo-1,4-dihydroquinoline-2-carboxylate | HCID 19735211 | — |
| Product | 7-Bromo-5-ethyl-4-oxo-1,4-dihydroquinoline-2-carboxylic acid | HCID 14842736 | — |
Reaction Steps
Treatment of ethyl 7-bromo-5-ethyl-4-oxo-1,4-dihydroquinoline-2-carboxylate with sodium hydroxide (0.247 g), as described in Example 1c, gave 7-bromo-5-ethyl-4-oxo-1,4-dihydroquinoline-2-carboxylic acid, mp 278° C. (decomp.). δ (360 MHz, DMSO-d6) 1.14 (3H, t, CH3), 3.24 (2H, q, CH2), 6.55 (1H, s, 3-H), 7.22 (1H, d, 6-H), 8.02 (1H, d, 8-H) and 11.74 (1H, bs, NH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05270309 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-53bf2cb740a34b2397f262077a9a2ad4 |
| Source note | uspto-grants-1993_12 |