HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 5,6,7-Trichloro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 19735172 | HCID 19735172 | — |
| Product | 5,6,7-Trichloro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid | HCID 14842712 | 75.1% |
Reaction Steps
Treatment of methyl 5,6,7-trichloro-4-oxo-1,4-dihydroquinoline-2-carboxylate (3 g) with sodium hydroxide (1.57 g) as described in Example 1c, gave 5,6,7-trichloro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (2.15 g). m.p. 290° C. (dec), δ (360 MHz, NAOD) 6.69 (1H, s, 3-H) and 7.66 (1H, s, 8-H) (Found: C, 40.90; H, 1.15; N, 4.78%, C10H4NO3Cl3 requires C, 41.06; H, 1.38; N, 4.79%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05270309 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-480d2b00098742dcbe43013b0fcdabd4 |
| Source note | uspto-grants-1993_12 |