Trifluoroacetic acid → HCID 19735758, compound

HRID 326673Notes

Reaction equation

[CH2:1]([C:3]1[N:4]=[C:5]2[CH:10]=[CH:9][CH:8]=[C:7]([C:11]([C:13]3[CH:18]=[CH:17][C:16]([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=4[C:25]([O:27]C(C)(C)C)=[O:26])=[CH:15][CH:14]=3)=[O:12])[N:6]2[CH:32]=1)[CH3:2].FC(F)(F)C(O)=O>>[CH2:1]([C:3]1[N:4]=[C:5]2[CH:10]=[CH:9][CH:8]=[C:7]([C:11]([C:13]3[CH:18]=[CH:17][C:16]([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=4[C:25]([OH:27])=[O:26])=[CH:15][CH:14]=3)=[O:12])[N:6]2[CH:32]=1)[CH3:2]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 19735668HCID 19735668, compound

Product 1

HCID 19735758HCID 19735758, compound

Procedure

Prepared analogously to Example 1c from 2-ethyl-5-[(2'-(tert.butyloxycarbonyl)biphenyl-4-yl)carbonyl]-imidazo[1,2-a]pyridine and trifluoroacetic acid.

Sources & evidence

ORD record: ord-3e685a422a2a4ad69c2920127fe25876
Source dataset: uspto-grants-1993_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05270322

Reaction notes

Loading…