Phosphorus oxychloride → HCID 19735424, 화합물

HRID 326714노트

반응식

HRID 326714 반응식
[CH3:1][O:2][C:3]1[CH:20]=[CH:19][CH:18]=[CH:17][C:4]=1[CH2:5][CH:6]([C:12](OCC)=O)[C:7](OCC)=O.[ClH:21].[CH:22]([NH2:24])=[NH:23].P(Cl)(Cl)([Cl:27])=O>>[Cl:21][C:12]1[C:6]([CH2:5][C:4]2[CH:17]=[CH:18][CH:19]=[CH:20][C:3]=2[O:2][CH3:1])=[C:7]([Cl:27])[N:24]=[CH:22][N:23]=1

참가 물질

4

반응물 3

HCID 24813Phosphorus oxychlorideHCID 10313058Methanimidamide, hydrochloride (1:1)HCID 10612755HCID 10612755, 화합물

생성물 1

HCID 19735424HCID 19735424, 화합물

실험 절차

Reaction of diethyl o-methoxybenzylmalonate with formamidine hydrochloride yielded 5-(o-methoxybenzyl)-6-hydroxy-4(3H)-pyrimidione from which, by reaction with phosphorus oxychloride, there was obtained 4,6-dichloro-5-(o-methoxybenzyl)pyrimidine, melting point 95°-96° C.

후처리

  1. customyielded 5-(o-methoxybenzyl)-6-hydroxy-4(3H)-pyrimidione from which

출처 및 근거

ORD 기록
ord-ec1887262d414cf28671ca90a5d895e0
출처 데이터셋
uspto-grants-1993_12
특허 번호
US05270313

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