HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 1-(5.6-Dichloro-3-oxoindan-1-carbonyl)-2-(piperidinomethyl)piperidine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5,6-Dichloro-3-oxoindan-1-carbonyl chloride | HCID 15132407 | — |
| Reactant | 1-(2-Piperidinylmethyl)piperidine dihydrochloride | HCID 18914998 | — |
| Product | 1-(5.6-Dichloro-3-oxoindan-1-carbonyl)-2-(piperidinomethyl)piperidine hydrochloride | HCID 18915105 | 52% |
Reaction Steps
From 1.5 g of 2-(piperidinomethyl)piperidine dihydrochloride, 2.5 g of 5,6-dichloro-3-oxoindan-1-carbonyl chloride and 45 ml of 1N aqueous sodium hydroxide solution. 1.1 g of the title compound was obtained, melting at 240°-245° C. (dec), using a procedure similar to that in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05270327 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-787fd9d25b634d2898a2fbd5c2741d85 |
| Source note | uspto-grants-1993_12 |