HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → 2-Chloro-5-(pyrrolidine-1-sulfonyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | Benzoic acid, 2-chloro-5-[(methylamino)sulfonyl]- | HCID 111724 | — |
| Reactant | 2-Chloro-5-sulfino-benzoic acid | HCID 15112904 | — |
| Product | 2-Chloro-5-(pyrrolidine-1-sulfonyl)benzoic acid | HCID 2119874 | 91% |
Reaction Steps
The title compound was synthesised according to the procedure described for 2-Chloro-5-methylsulfamoyl-benzoic acid from 2-Chloro-5-sulfino-benzoic acid and pyrrolidine and obtained in 91% yield. MS (m/e): 288.0 (MH−, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427612B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-1e11387398a648819116aeffaedeb567 |
| Source note | uspto-grants-2008_09 |