HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyrrolidin-1-ylmethyl-piperidine → 1-(5,6-Dichloroindan-1-carbonyl)-2-(pyrrolidin-1-ylmethyl)piperidine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyrrolidin-1-ylmethyl-piperidine | HCID 2760541 | — |
| Reactant | 5,6-Dichloroindan-1-carbonyl chloride | HCID 18915166 | — |
| Product | 1-(5,6-Dichloroindan-1-carbonyl)-2-(pyrrolidin-1-ylmethyl)piperidine hydrochloride | HCID 18915045 | 32.6% |
Reaction Steps
From 1.18 g of 2-(pyrrolidin-1-ylmethyl)piperidine, and 1.87 g of 5,6-dichloroindan-1-carbonyl chloride. 0.51 g of the title compound was obtained melting at 245°-250° C. using a procedure similar to that in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05270327 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-ca0e569e6bd642e9810dd8b46d458dd6 |
| Source note | uspto-grants-1993_12 |