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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 32679Generated: October 25, 2026

Pyrrolidine → 5-(Propane-2-sulfonyl)-2-pyrrolidin-1-yl-benzoic acid

https://huagongshe.com/reaction/32679

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant2-Chloro-5-(propane-2-sulfonyl)benzoic acidHCID 43140999—
Reactant5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acidHCID 59793489—
Product5-(Propane-2-sulfonyl)-2-pyrrolidin-1-yl-benzoic acidHCID 5979361572%

Reaction Steps

The title compound was synthesised according to the procedure described for the synthesis of 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid from 2-Chloro-5-(propane-2-sulfonyl)-benzoic acid and pyrrolidine and obtained in 72% yield. MS (m/e): 296.2 (MH−, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07427612B2
Source datasetuspto-grants-2008_09
ORD IDord-a8c0e4b2b4cb4225b0741446d7242d22
Source noteuspto-grants-2008_09