HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Phenoxyethanimidamide → 4-Amino-2-(phenoxymethyl)pteridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Phenoxyethanimidamide | HCID 290245 | — |
| Reactant | 3-Aminopyrazine-2-carbonitrile | HCID 817699 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Amino-2-(phenoxymethyl)pteridine | HCID 10634626 | — |
Reaction Steps
Obtained using the procedure described in section c of Example 2, starting with 3.0 g (0.025 mole) of 3-amino-2-pyrazinecarbonitrile and 3.8 g (0.025 mole) of 2-phenoxyacetamidine [prepared according to C. Djerassi and C. R. Scholz, J. Am. Chem. Soc., 1947, 69, 1688] in 100 ml if absolute ethanol. Refluxing time: 4 hours. Yld: 5.4 g (85%), m.p. 202°-204° C. (ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05270465 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-7b86348f449d4ec3a65074b66d295caa |
| Source note | uspto-grants-1993_12 |