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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 326857Generated: October 31, 2026

3-Aminopyrazine-2-carbonitrile → HCID 10731668, compound

https://huagongshe.com/reaction/326857

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Aminopyrazine-2-carbonitrileHCID 817699—
Reactant2-(4-Methoxyphenoxy)ethanimidamideHCID 10654955—
ReactantN,N-dimethylformamide ethanolHCID 19794673—
SolventEthanolHCID 702—
ProductHCID 10731668HCID 10731668—

Reaction Steps

Obtained using the procedure described in section c of Example 2, starting with 9.8 g (0.082 mole) of 3-amino-2-pyrazinecarbonitrile and the above solution of 2-(4-methoxyphenoxy)acetamidine in absolute ethanol. Refluxing time: 2 hours. Yld: 5.5 g (24%), m.p. 238°-240° C. (ethanol/N,N-dimethylformamide).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05270465
Source datasetuspto-grants-1993_12
ORD IDord-eab668f2645641b4b8e48be7273810d4
Source noteuspto-grants-1993_12